Resume
Name | Haibo He | Gender | male | 
|
Age | 53 years | Date of birth | 1972.01 |
Departments | College of Biological and Pharmaceutical Sciences, China Three Gorges University |
Education | Ph.D. | Title | Professor |
Telephone | 13469861312 | E-mail | hehaibo252219@163.com |
He Haibo, Ph.D. of China Pharmaceutical University, postdoctoral of Zhejiang University, professor and master’s supervisor, postdoctoral of Toyama University of Japan, young member of the basic theory branch of traditional Chinese medicine of Chinese medicine society, executive director of the World Federation of Chinese medicine diet and dietotherapy research professional committee, vice president of Yichang pharmaceutical society, distinguished professor of the second people's Hospital of Three Gorges University and Affiliated Hospital of traditional Chinese medicine. It is mainly engaged in the extraction and separation of natural products, the screening of active ingredients and the research of action mechanism, the research of tumor targeting nano preparations, the development of functional food, health products and new drugs. In recent years, he has presided over 10 national, provincial and ministerial projects, established one Yichang Key Laboratory, 5 horizontal projects, published more than 70 scientific research papers, including more than 30 SCI research papers of the first and corresponding author (3 in one area), with a cumulative impact factor of 50.136 (2.562 each), and the highest single paper of 6.200. The total number of citations reached 425, 3 papers were listed as “ESI highly cited papers”, and 3 monographs were edited. It has won one third prize of Hubei Province Science and technology progress award, one third prize of Chinese Academy of traditional Chinese medicine science and technology progress award, two first prize of Yichang City Science and technology progress award, and authorized six invention patents; participated in the research and development of three new drugs, completed the research and development of five health products and 10 functional foods, and completed the research and development of four hospital preparations. |
Education experience | Time | Universities and Colleges | Specialities | Education |
2003/09-2006/06 | China Pharmaceutical University | Pharmacology | Ph.D. |
2000/09-2003/06 | Hunan University of traditional Chinese Medicine | Chinese pharmacy | Master |
1992/09-1995/06 | China Three Gorges University | Chinese pharmacy | Bachelor |
Research experience | Time | Universities and Colleges | Department | Office |
2022/01-present | China Three Gorges University | College of Biological and Pharmaceutical Sciences | Professor |
2019/05-2021/12 | China Three Gorges University | College of Biological and Pharmaceutical Sciences | Associate professor |
2018/04-2019/04 | Toyama University of Japan | Institute of Natural Medicine, Postdoctoral | Researcher |
2014/07-2018/03 | China Three Gorges University | College of Biological and Pharmaceutical Sciences | Associate professor |
2008/08-2014/06 | China Three Gorges University | College of Biological and Pharmaceutical Sciences | Lecturer |
2006/07-2008/07 | Zhejiang University | College of Pharmacy, Postdoctoral | Researcher |
1995/07-2000/08 | The Third Hospital of Ezhou City, Hubei Province | Pharmacy Department
| Director |
Scientific research projects in the last five years
l Cooperation project of Xudan Biotechnology (Yuan’an) Co., Ltd, SDHZ20240339, Key technological innovation and industrialization in the research and development of medicinal and edible health products, 2024/05-2029/05, 1000000 yuan, under research and presided over;
l Cooperation project of Hubei Heng’an Fulin Pharmaceutical Co., Ltd, SDHZ20240164, Innovation and Industrialization of Key Technologies for Ecological Planting, Processing, and Utilization of Medicinal Materials in Hubei Province, 2023/01-2027/12, 5000000 yuan, under research and presided over;
l Key Project of Natural Science Foundation of Hubei Provincial Department of Science and Technology, 2022BBA097, Integration and Demonstration of Standardized Planting Technology in Qingjiang Ecological Tea Garden, 2023/01-2024/12, 300000 yuan, under research and presided over;
l Key Project of Natural Science Foundation of Hubei Provincial Department of Science and Technology, 2022BCE017, Study on the Mechanism and Application of Total Saponins from Zhuzishen, a Traditional Chinese Medicine with Western Hubei Characteristics, in Preventing and Treating Non alcoholic Fatty Hepatitis, 2023/01-2024/12, 300000 yuan, under research and presided over;
l General Program of Natural Science Foundation of Hubei Provincial Department of Science and Technology, 2022CFB357, Based on TLR4/NF-κB/NLRP3 inflammasome pathway mediates inflammatory cell immune inflammatory activation. The mechanism of papaya total triterpenoids in treating RA, 2023/01-2024/12, 50000 yuan, under research and presided over;
l Cooperation Project of Wenzhou Seventh People's Hospital in Zhejiang Province, SDHZ2022008, Exploring the Molecular Mechanism of Suanzaoren Hehuan Formula Saponins in Treating Depression and Insomnia Based on TLR4/NF-KB/NLRP3 Inflammatory Body Pathway Mediated Immunoinflammatory Regulation, 2021/01-2022/12, 50000 yuan, under research and presided over.
SCI papers published by the first author or corresponding author in recent 5 years
[1] Li Jie, He Junyu, He Haibo*, Wang Xiao, Zhang Shuran, He Yumin, Zhang Jihong, Yuan Chengfu, Wang Hongwu, Xu Daoxiang, Pan Chaowang, Xu Huifan, Zou Kun. Sweet triterpenoid glycoside from Cyclocarya paliurus ameliorates obesity-induced insulin resistance through inhibiting the TLR4/NF-κB/NLRP3 inflammatory pathway [J]. Curr Res Food Sci, 2024, 8(1): 100677. doi: 10.1016/j.crfs.2024.100677(IF: 6.200).
[2] Mengyao Wu, Junyu He, Yetao Chen, Fangzhu Wan, Hongbo Tang, Chenghong Yin, Haibo He*, Huifan Yu, Chengfu Yuan. Biomarkers for diagnosing and treating fetal growth restriction. Curr Med Chem, 2023, 25(10), doi: 10.2174/0109298673258444231019104656. (IF: 4.184)
[3] Junyu He, Jie Li, Yunayuan Zhang, Haibo He*, Yumin He, Daoxiang Xu, Xiao Wang, Hao yang Wu, Jihong Zhang, Hasan Jahid, Akter Sadia, Huifan Yu, Junzhi Wang, Kun Zou. Tormentic acid, a triterpenoid isolated from the fruits of Chaenomeles speciose, protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/ PKC/Rho a/MLC pathway. Pharm Biol, 2023, 61(1): 1343-1363(IF: 2.971).
[4] Shuran Zhang, Junyu He, Jie Li, Haibo He*, Yumin He, Xiao Wang, Heng Shu, Jihong Zhang, Daoxiang Xu, Kun Zou. Triterpenoid compounds from Cyclocarya paliurus: A review of their phytochemistry, quality control, pharmacology, and structure–activity relationship. Am J Chin Med, 2023, 51(11): doi: 10.1142/S0192415X2350088X(IF: 3.682).
[5] Haibo He, Minlu Feng, Haiyan Xu, Xiaomei Li, Yumin He, Huilin Qin, Yongfeng Zhang, Hongbo Tang, Kun Zou. Total triterpenoids from the fruits of Chaenomeles speciose protect indomethacin-induced gastric damage via modulating microRNA-423-5p and TFF/NAG-1 pathway. Food & Funct, 2020, 11(1):662-679 (IF: 4.171).
[6] Yuanyuan Zhang, Haiyan Xu, Haibo He*, Xiaomei Li, Minlu Feng, Yumin He, Weijie Jiang1, Junzhi Wang, Daoxiang Xu, Kun Zou. Total triterpenes from the fruits of Chaenomeles speciosa (Sweet) Nakai protects against indomethacin-induced gastric mucosal injury: involvement of TFF1-mediated EGF/EGFR and apoptotic pathways. J Pharm Pharmacol, 2019, doi: 10.1111/jphp.13207. (IF: 2.390).
[7] Xiaoqin Li, Hongbo Tang, Xiaoli Huang, Min Li, Ziwen Jiang, Haibo He*, Zhimin Zhou. Rigidity-dependent placental cells uptake of silk-based microcapsules. Macromol Biosci. 2019, 19(9): e1900105. doi: 10.1002/mabi.201900105 (IF: 4.306).
[8] Junzhi Wang, Ailing Wang, Haibo He*, Xinxin She, Yumin He, Shi Li, Lanqing Liu, Tao Luo, Nianyu Huang, Huajun Luo, Kun Zou. Trametenolic acid B protects against cerebral ischemia and reperfusion injury through modulation of microRNA-10a and PI3K/Akt/mTOR signaling pathways. Biomed Pharmacother, 2019, doi: 10.1016/j.biopha. 2019.108692 (IF: 3.457).
[9] Haibo He, Xiaomei Li, Haili Yu, Shu Zhu, Yumin He, Katsuko Komatsu, Dongyan Guo, Xiaoqin Li, Junzhi Wang, Huajun Luo, Daoxiang Xu, Kun Zou. Gastroprotective effect of araloside A on ethanol and aspirin-induced gastric ulcer in mice: involvement of H+/K+-ATPase and mitochondrial-mediated signaling pathway[J]. J Nat Med, 2019, 73 (2): 339-352 (IF: 1.920).
