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Communications Moibile Phone +86-13545708972
E-mail: huangny@ctgu.edu.cn
Address 8 University Avenue, 443002 Yichang, Hubei province, P.R. China
Experience July 2009 present: Instructor – China Three Gorges University
Hubei Key Laboratory of Natural Products Research and Development
College of Biological and Pharmaceutical Sciences
Yichang 443002, P. R. China
5/2015 - 5/2016: Visiting scholar– Methodology study in sugar chemistry
Division of Chemistry and BiologicalChemistry
School of Physical & MathematicalSciences
Nanyang Technological University
Education
n Ph. D. - Pesticidal Chemistry (Pesticide Molecule Design and Synthesis)
Key Lab of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University (9/2006 - 6/2009)
Title of Dissertation: “Synthetic Methods and Properties of Novel Guanines and other N-heterocycle Derivatives” (Supervisor: Prof. Ming-Wu Ding)
n M. S. – Organic Chemistry
(Successive postgraduate and doctoral programs of study; Supervisor: Prof. Ming-wu Ding)
College of Chemistry (9/2003 - 6/2006)
n B. S. – Applied Chemistry
College of Chemistry, Central China Normal University (9/1999 - 6/2003)
Areas of Interest Structure modification of natural products
Organic synthesis in heterocyclic chemistry
Bioactive molecular design and synthesis
Awards Third prize award on natural science in hubei province (2014, 2020)
Selected Articles
【1】Gang Chen, Guangjie Nie, Linxuan Li,* Jie Fu, Hui Yao, Nianyu Huang,* Nengzhong Wang*. Atom-Controlled Divergent Synthesis of Spiro and Fused Rings via Base-Catalyzed Chemoselective Annulation. Organic Chemistry Frontiers, 2025, 12, 2212-221. 【Impact factor: 5.4，Q1】
【2】 Yufei Zhang, Jing Chen, Hui Yao,* Yuanbin Wang, Hongyu Liu, Long Wang, Nianyu Huang,* Nengzhong Wang*. Phosphine-Catalyzed Divergent γ,γ- and ε,γ-Umpolung Domino Additions of Bisoxindoles with Allenoates: Construction of Vicinal All-Carbon Quaternary Stereocenters and Formal Total Synthesis of Dimeric Cyclotryptamine Alkaloids. Chinese Journal of Chemistry, 2025, 43, 995-1000. 【Impact Factor: 5.5，Q1】
【3】 Yangxing Sun, Keke Ren, Zhentao Zhang, Yanzhi Li, Nengzhong Wang, Hui Zeng, Nianyu Huang,* Xiao-Xi Li,* Wei-Qiao Deng, Hui Yao*. Palladium-Catalyzed O-Glycosylation through π–π Interactions. Organic Letters 2024, 26, 5396-5401. 【Impact Factor: 5.2，Q1】
【4】 Rui Xie, Jing Xu, Haolin Shi, Chenyu Xiao, Nengzhong Wang,* Nianyu Huang,* Hui Yao*. Stereocontrolled Synthesis of Aryl C-Nucleosides under Ambient Conditions. Organic Letters 2024, 26, 5162-5166. 【Impact Factor: 5.2，Q1】
【5】 Mengting Tan, Yunping Zheng, Sen Zhang, Hui Yao,* Xin Yan, Xing Zhao, Mingguo Liu, Nianyu Huang,* Nengzhong Wang*. Base-Controlled Chemodivergent [4+1] and [2+1]/[4+2] Annulations of o‑Aminochalcones with γ-Bromocrotonates. Organic Letters 2024, 26, 9203-9209. 【Impact Factor: 5.2，Q1】
【6】 Yi Li, Xianfei Hu, Boning Li, Sen Zhang, Hui Yao,* Xiao Xiao, Nianyu Huang,* Nengzhong Wang*. Controllable Phosphine-Catalyzed Three-Component Domino Reaction of Activated Alkenes with Morita-Baylis-Hillman (MBH) Carbonates: Divergent Synthesis of Densely Functionalized Cyclopentanes and Diquinanes. Organic Letters 2024, 26, 10651-10657. 【Impact Factor: 5.2，Q1】
【7】 Boning Li,‡ Xianfei Hu,‡ Hui Yao,* Yi Li, Dan Xu, Nianyu Huang,* Nengzhong Wang*. Pyridine-Catalyzed Chemoselective Four-Component Cascade Reaction of Aromatic Aldehydes, Malononitrile/Cyanoacetates, MBH Carbonates and Alcohols. Organic Letters 2024, 26, 7576-7583. 【Impact Factor: 5.2，Q1】
【8】 Zhengyang Chen, Dan Xiong, Nengzhong Wang,* Yufei Zhang, Hui Yao, Jinkun Zhang, Nianyu Huang,* Kun Zou*. Concise Synthesis of Pyrrolo[3,4-c]quinolines via a P(NMe2)3-Catalyzed [4+2] Annulation followed by a Zn/AcOH-Mediated Reduction-Hydroamination-Isomerization. Organic Chemistry Frontiers, 2024, 11, 2762-2767. 【Impact Factor: 5.4，Q1】
【9】 Shuhui Li, Xiaoxuan Li, Hui Yao*, Mengting Tan, Dan Xu, Nianyu Huang*, Nengzhong. Wang*, Straight-chain ω-amino-α,β-unsaturated carbonyl compounds: versatile synthons for the synthesis of nitrogen-containing heterocycles via organocatalytic reactions. Organic Chemistry Frontiers, 2024, 11, 236-253. 【Impact factor: 5.4，Q1】
【10】 Shuhui Li, Dan Xu, Hui Yao,* Mengting Tan, Xiaoxuan Li, Mingguo Liu, Long Wang, Nianyu Huang,* Nengzhong Wang*. Facile Synthesis of 2-Vinylindolines via a Phosphine-Mediated α-Umpolung/Wittig Olefination/Cyclization Cascade Process. Chemical Communications 2024, 60, 6773-6776. 【Impact Factor: 4.3，Q1】
【11】Yifei Huang, Mengting Tan, Nengzhong Wang*, Yufei Zhang, Hui Yao, Xiao Xiao, Nianyu Huang*, Kun Zou*. Highly Regio- and Diastereoselective Phosphine-Catalyzed [2 + 4] Annulation of Benzofuran-Derived Azadienes with Allyl Carbonates: Access to Spiro[benzofuran-cyclohexanes. The Journal of Organic Chemistry, 2023, 88, 13030-13041. 【Impact factor: 3.6，Q2】
【12】Xiaoxiao Zhao, Zhentao Zhang, Jing Xu, Nengzhong Wang*, Nianyu Huang*, Hui Yao*. Stereoselective Synthesis of O-Glycosides with Borate Acceptors, The Journal of Organic Chemistry, 2023, 88(16), 11735-11747.【Impact factor: 3.6，Q2】
【13】Jingyu Gao, Yi Li, Nengzhong Wang*, Zhiyue Li, Nianyu Huang*, Hui Yao*. One-Pot Stereoselective Synthesis of 2,3,4-Unprotected β-N-Glycopyranosides from Glycals and Amines. Advanced Synthesis & Catalysis, 2023, 365(14): 2350-2355.【Impact factor: 5.4，Q1】
【14】Mingyu Hou, Yimin Xiang, Jingyu Gao, Jingyu Zhang, Nengzhong Wang*, Haolin Shi, Nianyu Huang*, Hui Yao*. Stereoselective Synthesis of 2-Deoxy Glycosides via Iron Catalysis. Organic Letters 2023, 25(5), 832-837.【Impact Factor: 5.2，Q1】
【15】Yanyan Wang, Zhen Cao, Nengzhong Wang*, Mingguo Liu, Haifeng Zhou, Long Wang, Nianyu Huang*, Hui Yao*. Palladium-Catalyzed Stereospecific S-Glycosylation by Allylic Substitution. Advanced Synthesis & Catalysis 2023, 365(10), 1699-1704.【Impact factor: 5.4，Q1】
【16】 Jiayue Shi, Song Yang, Dongmei Zhang*, Nianyu Huang*, Shibing Ni*. C-Doped LiVO3 Honeycombs Derived from the Biomass Template Strategy for Superior Lithium Storage. Langmuir 2023, 39, 14074-14083. 【Impact factor: 3.9，Q2】
Issued patents inrecent years
【1】NianyuHuang, Junzhi Wang, Huajun Luo,Ximing Yan, LingWu, Chengqiao Cao, Zhangshuang Deng. A phenolic compound andits use. CN 201410495358.6
【2】NianyuHuang, Junzhi Wang, Chengqiao Cao,Wenbin Wang, Ximing Yan, Fan Zhang. Tetrahydrobenzothiazole-7-ketoxime drugs,preparation methods and application. CN 201510111459.3
【3】NianyuHuang, Mingguo Liu, Rongkun Li, JunzhiWang, Quanli Yang, Fan Zhang. A tetrahydroindole-4-ketoxime drug, itspreparation method and application. CN 201510118757.5
【4】NianyuHuang, Junzhi Wang, Kun Zou,Huajun Luo, Hubiao Fang, Wenbin Wang, Fan Zhang. A bistriazole acid inhibitor,its preparation method and application. CN 2015101276.0
【5】NianyuHuang, Wenbin Wang, LeiJin,FanZhang, Junzhi Wang, Kun Zou, Ximing Yan. Tetrahydrobenzofuran-4-ketoximetriazole drug, preparation method and application. CN 201510111498.3
